000			03702nam a22003497a 4500
003			BD-ChVAS
005			20260723100615.0
008			260723s2025 nyu||||| |||| 00| 0 eng d
020			_a9781032319193 _q(hardback)
020			_a9781032319223 _q(paperback)
020			_z9781003312048 _q(ebook)
040			_aBD-ChVAS _beng _eBD-ChVAS _cBD-ChVAS _dBD-ChVAS
082	0	0	_a615.9 _223 _bBOT
130	0		_aToxicologic pathology (Sahota) _93951
245	1	0	_aToxicologic pathology : _bnonclinical safety assessment / _cedited by Page Bouchard, Pritam Sahota, Shannon Wallace, Zbigniew Wojcinski, and Vanessa Schumacher ; illustrated by David A. Sabio.
250			_aThird edition.
260			_aNew York : _bCRC Press ; _cc2025.
300			_axv, 818 p. : _billas. ; _c26 cm.
504			_aIncludes bibliographical references and index.
505	0		_aNonclinical Safety Assessment : An Overview of Drug and Medical Device Development / Thomas M. Monticello, Timothy MacLachlan, Kathleen A. Funk, Brooke M. Rock, Jeanine L. Bussiere, Jessica Grieves, JoAnne C.L. Schuh, and Scott Henry -- Toxicologic Anatomic Pathology and the Pathologist / Vanessa L. Schumacher, Christopher J. Clarke, Robert C. Johnson, Arun R. Pandiri, and Daniel J. Patrick -- Toxicologic Clinical Pathology / Niraj K. Tripathi -- Gastrointestinal System / Thomas Nolte, Jagannatha Mysore, Arlin Rogers, and Johannes Junginger -- Hepatobiliary System and Exocrine Pancreas / Arun R. Pandiri, Barbara Lenz, and Christopher D. Houle -- Respiratory System / Tom P. McKevitt and Nicholas Macri -- Urinary System / Kendall S. Frazier and John Curtis Seely -- Hematopoietic System / Kristin L. Henson, Tanasa S. Osborne, Allison Vitsky, and Adi Wasserkrug-Naor -- Lymphoid System / Patrick Haley -- Musculoskeletal System and Teeth / Kathryn E. Gropp, Agathe Bédard, Stacey Fossey, D. Greg Hall, and Ryan M. Schafbuch -- Cardiovascular System / Ronnie Chamanza, Chidozie Amuzie, David Brott, and Calvert Louden -- Endocrine System / Richard A. Peterson, Christopher Houle, and Raju Mantena -- Reproductive System and Mammary Gland / Justin D. Vidal, Sarah Coe, Karyn Colman, Kiran Palyada, Cynthia J. Willson, and Charles E. Wood -- Integumentary System / Zbigniew W. Wojcinski, Lydia Andrews-Jones, Daher Ibrahim Aibo, Rie Kikkawa, Sheila Cummings, and Robert Dunstan -- Nervous System / Sarah D. Cramer, Alys Bradley, and Mark T. Butt -- Special Senses : Eye and Ear / Vanessa Vrolyk, Kenneth A. Schafer, Oliver C. Turner, Helen S. Booler, and Richard A. Altschuler.
520			_a"The new edition provides practical and timely information for toxicologic pathologists working in drug discovery and development. The introductory concept chapters are consolidated into two more concise and better organized introductory chapters. The two concept chapters introduce the reader to pharmaceutical R&D, the role of the pathologist in the process, and critical partner scientific disciplines with whom the pathologist will collaborate. In this revision, the organ system chapters incorporate more consistent commentary and guidance on the molecular mechanism of action, human translational relevance, and regulatory impact of pathological findings as they are described in these chapters"--
650	1	2	_aDrug Evaluation, Preclinical _93952
650	2	2	_aRisk Assessment _93953
650	2	2	_aToxicity Tests _93954
700	1		_aBouchard, Page R., _eeditor. _93955
700	1		_aSahota, Pritam S., _eeditor. _93956
700	1		_aWallace, Shannon, _eeditor. _93957
700	1		_aWojcinski, Zbigniew W., _eeditor. _93958
700	1		_aSchumacher, Vanessa L. _eeditor. _93959
700	1		_aSabio, David A., _eillustrator. _93960
942			_2ddc _cBKR
999			_c3481 _d3481