000			02986nam a22002657a 4500
003			BD-ChVAS
005			20260709131035.0
008			260709b |||||||| |||| 00| 0 eng d
020			_a9781032660769 _q(hardback)
020			_a9781032660738 _q(paperback)
020			_z9781032660752 _q(ebook)
040			_aBD-ChVAS _beng _eBD-ChVAS _cBD-ChVAS _dBD-ChVAS
082	0	0	_a616.0277 _223 _bTAC
100			_aTay, Andy Kah Ping, _93868
245	0	0	_aCAR -T manufacturing : _btechnologies and innovations / _cedited by Andy Kah Ping Tay.
250			_aFirst edition.
260			_aNew York : _bCRC Press ; _cc2025.
300			_avii, 111 p. : _bill., table ; _c22 cm .
504			_aIncludes bibliographical references and index.
505	0		_aImmune cell selection and Isolation / Jessalyn Low, Andy Tay -- Strategies for T cell Activation / Jessalyn Low, Andy Tay -- Genetic tools to engineer CAR-T cells : Lessons from clinical studies / Yu Yang Ng, Andy Tay -- Intracellular delivery methods for therapeutic immune T-cell engineering / Arun R. K. Kumar, Andy Tay -- Bioreactor technology for CAR T cell manufacturing / Yi Kai Luo, Andy Tay -- Quality Control of CAR-T Products / Jerome Adriel Tjiptadi, Andy Tay -- Advances for in vivo CAR-T manufacturing / Mohamed Bilal S/O Saibudeen, Kenneth Goh Jun Lim, Andy Tay.
520			_a"This edited volume describes innovations in all steps of the CAR-T manufacturing chain. These vital descriptions will help practitioners to overcome current challenges during the process and vastly reduce costs and enable timely and accessible administration of CAR-T therapy to patients. The book provides readers with information on key fundamental concepts of CAR-T manufacturing in areas such as cell selection, cell activation, cell transfection, cell expansion, genetic engineering, and quality control. In each chapter, different experts cover a particular technological field in the CAR-T manufacturing chain. Each chapter will include an introduction to the importance of a particular technology for cell manufacturing, comparisons of state-of-the-art methods, and discussions on emerging innovations of that particular technology. This exposes readers to a high-level view of the entire process while diving into details for each specific process step. Readers will be able to apply their knowledge to make changes at each step of the CAR-T manufacturing process to reduce the currently high costs and long production times, so that cancer patients globally can benefit from CAR-T therapy. This book is an invaluable resource for practitioners in CAR-T manufacturing who aim to improve their quality and efficiency while reducing time and costs. It is also useful for advanced undergraduate and graduate students who wish to gain a strong foundation for continuing research in the field or interacting with practitioners"--
650	1	2	_aImmunotherapy, Adoptive _xmethods _93869
650	2	2	_aCell Engineering _xmethods _93870
942			_2ddc _cBKR
999			_c3450 _d3450