Biotechnology and biopharmaceuticals : transforming proteins and genes into drugs / Rodney J.Y. Ho, Milo Gibaldi. - Hoboken, N.J. : Wiley-Liss, c2003. - xvii, 556 p. : ill. ; 26 cm.
Includes bibliographical references and index.
Introduction to biopharmaceuticals -- Comparative drug development of proteins and genes versus small molecules -- Biotechnology industry perspective on drug development -- Biopharmaceutical technologies and processes in drug development -- Pharmacology, toxicology, therapeutic dosage formulations, and clinical response -- Hematopoietic growth factors and coagulation factors -- Interferons and cytokines for anti-infective and cancer therapy -- Hormones -- Enzymes -- Antibodies and derivatives -- Vaccines -- Other products : monographs -- Advanced drug delivery -- Individualization of drug regimens : integration of pharamacokinetic and pharmacogenic principles in drug therapy -- Gene and cell therapy -- Integration of discovery and development : the role of genomics and proteomics.
RS380 / .H6 2003